CLOUDFLARE, DATABRICKS PARTNERSHIP TO BRING MLFLOW CAPABILITIES TO DEVELOPERS

KUALA LUMPUR, Sept 29 (Bernama) — Cloudflare Inc has announced a continued collaboration with Databricks, the Data and artificial intelligence (AI) company, to bring MLflow capabilities to developers building on Cloudflare’s serverless developer platform.

“Together with Databricks we can offer a comprehensive and optimized platform to support a wide spectrum of AI workflows, models and applications,” said Cloudflare chief executive officer and co-founder, Matthew Prince.

Cloudflare is joining the open source MLflow project as an active contributor to bridge the gap between training models and easily deploying them to the company’s global network, where AI models can run close to end-users for a low-latency experience.

In this new phase of partnership and collaboration on MLflow, an open-source platform for managing the machine learning (ML) lifecycle created by Databricks, Cloudflare and Databricks are closing the loop on how AI models are quickly and easily deployed to the edge.

With this new partnership, developers will be able to train models utilising Databricks’ data-centric AI platform, then deploy those models to Cloudflare’s developer platform and global network, where hyper-local inference is deployed on the edge, to complete the AI lifecycle.

Developers building on Cloudflare Workers AI will be able to leverage MLflow compatible models for easy deployment into Cloudflare’s global network, while also able to use MLflow to efficiently package, implement, deploy and track a model directly into Cloudflare’s serverless developer platform.

According to a statement, Databricks and Cloudflare already collaborate to simplify the AI lifecycle by making sharing data simpler and more affordable through Delta Sharing with R2 storage.

Cloudflare’s R2 is a zero egress, distributed object storage offering, allowing data teams to share live data sets and AI models with Databricks, easily and efficiently, eliminating the need for complex data transfers or duplications of data sets, and with zero egress fees.

A connectivity cloud company, Cloudflare empowers organisations to make their employees, applications and networks faster and more secure everywhere, while reducing complexity and cost.

— BERNAMA

AM Best Affirms Taiwan’s Cathay Century Credit Ratings As Excellent

KUALA LUMPUR, Sept 29 (Bernama) — Global credit rating agency, AM Best has affirmed the Financial Strength Rating of A (Excellent) and the Long-Term Issuer Credit Rating of “a” (Excellent) of Taiwan’s Cathay Century Insurance Company Limited (Cathay Century).

In a statement, AM Best said the credit ratings (ratings), which have a stable outlook, reflected Cathay Century’s balance sheet strength, which was assessed as very strong, as well as its adequate operating performance, neutral business profile and appropriate enterprise risk management.

Cathay Century’s risk-adjusted capitalisation, as measured by Best’s Capital Adequacy Ratio, was at the very strong level at year-end 2022 and is expected to strengthen gradually over the short to intermediate term and be commensurate with the pre-pandemic level through earnings retention.

Other supportive factors of the balance sheet strength assessment include the company’s diversified investment portfolio that focuses on low-risk fixed-income securities, good liquidity, and comprehensive reinsurance arrangements.

Cathay Century remains the second-largest insurer in Taiwan’s non-life sector, with a market share of 12.8 per cent in terms of direct premiums written (DPW) in 2022. The company’s underwriting portfolio is diversified moderately with motor being a major line of business, accounting for over half of the company’s DPW in 2022, followed by fire, accident and health businesses.

The portfolio is skewed toward personal lines insurance products and the company continues to leverage the comprehensive business network of its parent group and affiliated distribution channels to grow its underwriting portfolio.

In addition, Cathay Century has refined and strengthened its risk management by reviewing product design and underwriting control, following the significant pandemic insurance claims. Cathay Financial Holding also has collaborated with Cathay Century to provide risk oversight support and resources.

— BERNAMA

Cloudflare Partners Microsoft To Enable AI Model Location

KUALA LUMPUR, Sept 29 (Bernama) — Cloudflare Inc, the connectivity cloud company, has collaborated with Microsoft to make it easier for companies to run artificial intelligence (AI) in the location most suitable for their needs.

“Together, Cloudflare and Microsoft will build the railroad tracks that AI traffic and tasks will move on, to tailor AI inference to the exact needs and demands of every organisation,” said its chief executive officer and co-founder, Matthew Prince in a statement.

Meanwhile, Microsoft General Manager of Data, AI, & Emerging Technologies, Rashmi Misra said: “With Cloudflare’s combination with Microsoft’s experience in training and deploying the world’s most advanced AI workloads through our Azure cloud, businesses will gain access to a new level of flexibility and performance for AI inference.”

As inference tasks become more and more distributed, this collaboration will enable businesses to seamlessly deploy AI models across a computing continuum that spans device, network edge, and cloud environments, maximising the benefits of both centralised and distributed computing models.

By leveraging ONNX Runtime, a cross-platform accelerated machine learning, across these three tiers, Cloudflare and Microsoft can ensure that AI models can be run anywhere.

AI model training requires significant computational and storage resources in close proximity to one another, making centralised cloud platforms the best environment for the intensive calculations needed in model training.

While training will continue to be centralised, inference tasks will be increasingly performed in more distributed locations, specifically on devices themselves and on edge networks.

Microsoft’s AI capabilities and hyperscale cloud infrastructure combined with Cloudflare’s hyper-distributed edge network will empower businesses to drive innovation and efficiency across the entire AI lifecycle.

As a result, businesses will be able to find the best location for AI tasks; navigate changing needs; and deploy on Cloudflare in a few clicks.

— BERNAMA

TechTarget Archer Awards Honours Tech Marketing, Sales Leaders In APAC

KUALA LUMPUR, Sept 26 (Bernama) — TechTarget Inc, the global leader in business-to-business (B2B) technology purchase intent data and marketing services, has recognised noteworthy technology marketing and sales leaders across Asia Pacific (APAC) with its 2023 Archer Awards.

According to a statement, each of the winners is fuelling highly successful marketing and sales initiatives leveraging real Prospect-Level Intent data.

TechTarget Chief Executive Officer, Michael Cotoia said Intent data is essential for the modern marketer and sales professional to focus their efforts on the right accounts and to influence all members of the buying team.

“This select group of organisations are taking the smart approach. The winners are using intent data to power a wide array of digital advertising, demand gen, content marketing and sales engagement programmes that are delivering a significant impact to their businesses,” he said.

The 2023 Archer Award APAC winners are CrowdStrike APJ (Digital Marketer of the Year); Cloudflare APJC (Digital Team of the Year); DocuSign APJ (Priority Engine Marketing Team of the Year); Okta APAC (Priority Engine Sales Team of the Year); Palo Alto Networks JAPAC (Best Demand Generation Program); and Hewlett Packard Enterprise APJ (Best Multimedia Program).

Currently in its fourth year, the Archer Awards which developed by TechTarget recognises achievements across North America, Europe and APAC.

By creating abundant, high-quality editorial content across more than 150 highly targeted technology-specific websites and over 1,100 channels, TechTarget attracts and nurtures communities of technology buyers researching their companies’ information technology needs.

— BERNAMA

ANAQUA UNVEILS EXECUTIVE LEADERSHIP CHANGES, HEADQUARTERS OPENING IN JAPAN

KUALA LUMPUR, Sept 26 (Bernama) — Anaqua, the global innovation and intellectual property (IP) management technology provider, has appointed Futoshi Saito as its President & General Manager, effective Oct 10.

According to Anaqua in a statement, Saito will be responsible for driving Anaqua’s ongoing business development and delivering enhanced client solutions in Japan, marking changes to its executive leadership team in Japan.

“His extensive IP and technology experience will enable him to engage quickly with our business and the wider market, forming important relationships with our existing and future clients, and providing strong leadership for our team and our further business development,” said its Chief Executive Officer, Bob Romeo.

Meanwhile, Saito said: “I am honoured to lead Anaqua Japan through its next stage of growth and to help our clients better protect and maximise value from their IP portfolios.”

Saito previously held leadership positions at LexisNexis as Managing Director, Japan and South Korea, and Thomson Reuters (now part of Clarivate) as head of the IP & Science business in Japan.

He holds a bachelor’s degree in international studies from Dokkyo University and studied at the Graduate School of History at the State University of New York at Albany.

On the other hand, the company also announced the opening of its new Japan headquarters in the TOKYO TORCH Tokiwabashi Tower, providing an expanded work space to support its accelerated growth, which has seen further strengthening of the team and a 50 per cent increase in new sales year to date.

The move continues Anaqua Japan’s mission to invest in people, infrastructure and solutions in order to provide clients with the most comprehensive and effective IP management software and solutions in Japan.

— BERNAMA

CLOUDFLARE HELPS COMPANIES REDUCE THEIR IT INFRASTRUCTURE’S CARBON FOOTPRINT BY UP TO 96% BY MOVING TO THE CLOUD

New report finds that switching enterprise network services from on premises devices to Cloudflare services can cut related carbon emissions up to 96%

SAN FRANCISCO, Sept 26 (Bernama-BUSINESS WIRE) — Cloudflare, Inc. (NYSE: NET), the security, performance, and reliability company helping to build a better Internet, today shared a new independent report published by Analysys Mason that shows switching enterprise network services from on premises devices to Cloudflare’s cloud-based services can cut related carbon emissions up to 78% for very large businesses to up to 96% for small businesses. The report is one of the first of its kind to calculate potential emissions savings achieved by replacing enterprise network and security hardware boxes with more efficient cloud services.

Global Internet usage accounts for 3.7% of global CO2 emissions, about equal to the CO2 emissions of all air traffic around the world. The Internet needs to reduce its overall energy consumption, especially as regulators continue to implement the Paris Climate Accord, including plans to transition to a zero emissions economy. The European Climate Law requires that Europe’s economy and society become climate-neutral by 2050, with a target of reducing net GHG emissions by at least 55% by 2030, compared to 1990 levels. Regulators in the United States and the European Union, among others, have also announced plans to require companies to disclose climate-related information including carbon emissions resulting from their operations and supply chains, as well as climate related risks and opportunities. Finally, among the Fortune Global 500, 63% of companies now set 2050 targets for emissions reductions. Companies large and small will increasingly be looking to reduce carbon throughout their supply chains, particularly their IT infrastructure.

“The best way to reduce your IT infrastructure’s carbon footprint is easy: move to the cloud,” said Matthew Prince, CEO and co-founder, Cloudflare. “At Cloudflare, we’ve built one of the world’s most efficient networks, getting the most out of every watt of energy and every one of our servers. That’s why, with Cloudflare, companies can help hit their sustainability goals without sacrificing security, speed, performance, or innovation.”

The Analysys Mason study found that switching enterprise network services from on premises devices to Cloudflare services can cut related carbon emissions up to 96%, depending on the current network footprint. The greatest reduction comes from consolidating services, which improves carbon efficiency by increasing the utilization of servers that are providing multiple network functions. On premises devices are designed to host multiple workloads and consume power constantly, but are only used for part of the day and part of the week. Cloud infrastructure is shared by millions of customers, often all over the world. As a result, cloud providers are able to achieve economies of scale that result in less downtime, less waste, and lower emissions. Furthermore, the Analysys Mason study found that there are additional gains due to the high Power Usage Effectiveness of cloud data centres, and differences in the carbon intensity of generation in the local electricity grid.

​“Happy Cog is a full-service digital agency that designs, builds, and markets experiences that engage our clients and their audiences. We’ve relied on Cloudflare for many of those websites and apps because it’s secure, reliable, fast, and affordable – but also aligns with many of our clients’ sustainability roadmaps and goals,” said Matt Weinberg, Co-Founder and President of Technology at Happy Cog. “Switching our clients from their previous on premises or other constant-usage infrastructure to Cloudflare’s network and services has let them be greener, more efficient, and more cost effective. It’s ideal when you can offer your clients a solution that covers all their needs and provides a delightful experience now, without having to compromise on their longer term priorities.”

Report Methodology

Analysys Mason compared a typical hardware stack deployed in an enterprise data center or IT closet, and its associated energy consumption, to the energy consumption of comparable functions delivered by Cloudflare’s global network. Traffic requirements were translated to energy requirements for both on-premise and cloud-based alternatives. The analysis includes assumptions for the power usage effectiveness (PUE) of cloud data centers vs. on-premises data centers or data rooms, and the carbon from electricity, based on the mix of fossil fuel versus renewable energy sources in the local grid.

To learn more, please check out the resources below:

About Cloudflare

Cloudflare, Inc. (www.cloudflare.com / @cloudflare) is on a mission to help build a better Internet. Cloudflare’s suite of products protect and accelerate any Internet application online without adding hardware, installing software, or changing a line of code. Internet properties powered by Cloudflare have all web traffic routed through its intelligent global network, which gets smarter with every request. As a result, they see significant improvement in performance and a decrease in spam and other attacks. Cloudflare was awarded by Reuters Events for Global Responsible Business in 2020, named to Fast Company’s Most Innovative Companies in 2021, and ranked among Newsweek’s Top 100 Most Loved Workplaces in 2022.

Forward-Looking Statements

This press release contains forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which statements involve substantial risks and uncertainties. In some cases, you can identify forward-looking statements because they contain words such as “may,” “will,” “should,” “expect,” “explore,” “plan,” “anticipate,” “could,” “intend,” “target,” “project,” “contemplate,” “believe,” “estimate,” “predict,” “potential,” or “continue,” or the negative of these words, or other similar terms or expressions that concern Cloudflare’s expectations, strategy, plans, or intentions. However, not all forward-looking statements contain these identifying words. Forward-looking statements expressed or implied in this press release include, but are not limited to, statements regarding Cloudflare’s plans and objectives for its global network and other products and technology, the benefits to customers from using Cloudflare’s global network and other products and technology, the expected functionality and performance of Cloudflare’s global networkand other products and technology, the impact of switching enterprise network services to the cloud, Cloudflare’s technological development, future operations, growth, initiatives, or strategies, and comments made by Cloudflare’s CEO and others. Actual results could differ materially from those stated or implied in forward-looking statements due to a number of factors, including but not limited to, risks detailed in Cloudflare’s filings with the Securities and Exchange Commission (SEC), including Cloudflare’s Quarterly Report on Form 10-Q filed on August 3, 2023, as well as other filings that Cloudflare may make from time to time with the SEC.

The forward-looking statements made in this press release relate only to events as of the date on which the statements are made. Cloudflare undertakes no obligation to update any forward-looking statements made in this press release to reflect events or circumstances after the date of this press release or to reflect new information or the occurrence of unanticipated events, except as required by law. Cloudflare may not actually achieve the plans, intentions, or expectations disclosed in Cloudflare’s forward-looking statements, and you should not place undue reliance on Cloudflare’s forward-looking statements.

© 2023 Cloudflare, Inc. All rights reserved. Cloudflare, the Cloudflare logo, and other Cloudflare marks are trademarks and/or registered trademarks of Cloudflare, Inc. in the U.S. and other jurisdictions. All other marks and names referenced herein may be trademarks of their respective owners.

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CERTIK FORGES PARTNERSHIP WITH CROSSANGLE (XANGLE) TO ELEVATE WEB3 SECURITY AND DATA TRANSPARENCY

New York, Sept 20 (Bernama-GLOBE NEWSWIRE) — CertiK, a leader in Web3 security and CrossAngle, the Web3 data intelligence provider behind the Xangle platform today announced a landmark strategic partnership to raise the standards of security and transparency across the Web3 ecosystem.

Through this partnership, CrossAngle will feature CertiK research reports on the Xangle platform, which is available in both English and Korean. These reports provide users with critical insights, deepening their understanding of the crypto landscape and supporting Web3 mass adoption

Additionally, CertiK will integrate Xangle’s comprehensive API data, which encompasses market prices, weighted indices, project profiles, and research reports. In return, CertiK will offer Xangle access to security data from Skynet, an all-in-one security insights dashboard for over 10,000 Web3 platforms.

“We are thrilled to partner with Xangle, a leader in Web3 data analytics,” said Jason Jiang, Chief Business Officer at CertiK. “This collaboration not only underscores our mutual commitment to enhancing security and transparency in the blockchain space but also paves the way for a more informed and secure Web3 ecosystem. Together, we aim to set new industry standards, ensuring that users and projects have access to the best resources and data-driven insights.”

Jake Lim, Xangle’s Chief Business Development Officer, also expressed his excitement:, “We are very pleased to establish this partnership with CertiK. We anticipate the synergy that it will create with Xangle’s strong on-chain data analysis capabilities.” He further believes that “the collaboration between Xangle and CertiK will contribute to advancing the ongoing mass adoption of Web3.”

Both entities are committed to fostering a sustainable, reliable, and user-friendly Web3 ecosystem. This partnership underscores their mutual dedication to this vision, with a focus on data-driven insights and top-tier security.

About CertiK

CertiK is a pioneer in blockchain security, combining expert manual review with best-in-class AI technology to protect and monitor blockchain protocols and smart contracts. Founded in 2018 by professors from Yale University and Columbia University, CertiK’s mission is to secure the web3 world. CertiK applies cutting-edge innovations from academia to enterprise, enabling mission-critical applications to scale with safety and correctness.

One of the fastest-growing and most trusted companies in blockchain security, CertiK is a true market leader. To date, CertiK has worked with nearly 4,000 enterprise clients, secured over $360 billion worth of digital assets, and has detected almost 70,000 vulnerabilities in blockchain code. Our clients include leading projects such as Aptos, Ripple, Sandbox, Polygon, BNB Chain, and TON.

​​CertiK is backed by InsightPartners, Sequoia, Tiger Global, Coatue Management, Lightspeed, Advent International, SoftBank, Hillhouse Capital, Goldman Sachs, Coinbase Ventures, Binance, Shunwei Capital, IDG Capital, Wing, Legend Star, Danhua Capital and other investors.

About CrossAngle

CrossAngle, the operator of the global Web3 data intelligence platform Xangle, has committed itself to resolving information asymmetry within the blockchain ecosystem and achieving mass adoption of Web3 since its founding in 2018. Over the years, CrossAngle has consistently released high-quality industry analysis reports with the goal of fostering a transparent and robust Web3 industry environment. The reports have earned recognition for their expertise and have been featured on prominent local and global crypto and financial information platforms, including Bloomberg Terminal, CoinMarketCap , Yonhap Infomax, and FnGuide.

In April 2022, Xangle achieved a significant milestone by securing a Series B investment from established traditional financial institutions, including KB Investment and Shinhan Capital Investment. Xangle has gained widespread recognition as a leading industry player in the Web3 industry, focusing on industry analysis and infrastructure provision. As part of its mission to promote Web3 adoption, Xangle is gearing up to launch two key products this year – “Explorer,” designed for on-chain data search and analysis, and “Xangle Beacon,” a comprehensive Web3 ERP solution.

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2023 年度 Stevie 杰出雇主奖得主揭晓

Bank of America 和 Globe Telecom 跻身获奖者前列

弗吉尼亚州费尔法克斯, Sept 21 (GLOBE NEWSWIRE) — 一场国际性奖项的角逐落下帷幕——2023 年Stevie® “杰出雇主奖”得主于本周一(9 月 18 日)在纽约市举行的颁奖典礼上揭晓。该奖项旨在表彰世界上最优秀的雇主和人力资源专业人员、团队、成就以及与人力资源相关的产品和供应商,他们帮助创造和推动了良好的的职场环境。

Stevie 金奖、银奖和铜奖得主的完整名单(按类别分类)可在以下网址查阅:http://www.StevieAwards.com/HR.

获奖者包括世界各地多元化的组织和个人。Stevie 年度最高荣耀组织杰出奖由总部位于美国北卡罗莱纳州夏洛特的 Bank of America 获得,该组织总计获得 7 项金奖、7 项银奖和 7 项铜奖,共计得分为 45.5 分。“年度组织奖”颁发给获得最多奖项积分的组织。参赛组织每获得一项 Stevie 金奖得 3 分;每获得一项 Stevie 银奖得 2 分;每获得一项 Stevie 铜奖得 1.5 分。

Stevie 杰出奖“年度最高分提名奖”的获奖者是总部位于菲律宾达义市的 Globe Telecom Inc.。来自该组织的 Ato Jiao 被提名为年度最佳首席人力资源官,并在评审团评审中获得了 9.5 的高分(满分为 10 分)。

获得 Stevie 金奖最多的组织包括 Bank of America (7)、Cathay United Bank (5) IBM (4)、Tata Consultancy Services (4)、Tech Mahindra (4)、Dimes Sanayi ve Ticaret A.Ş.(3)、Enerjisa Enerji (3)、TELUS International (3)、Akbank T.A.S.(2)、American Systems (2)、Ayala Land Inc. (2)、BlueSky Personnel Solutions (2)、Borusan (2)、DHL Global Forwarding、Freight (2)、FedEx (2)、Globe Telecom (2)、GoHealth (2)、Golden Hour Veterinary Telemedicine (2)、Kordsa Teknik Tekstil A.Ş.(2)、Saint-Gobain North America (2)、Siemens AG (2)、以及 Top Hat (2)。

在今年的角逐中,来自 28 个国家/地区的 1,000 余个组织的提名接受了评估。获奖者由来自全球各地的超过 125 位担任评委的专业人士给出的平均分决定。

“年度最佳雇主”类别下的 31 个 Stevie 奖项则采用了另一种独特的评选模式,综合考虑专业评委的评分以及公众投票的结果决定获奖者。

Stevie “杰出雇主奖”旨在表彰在得主们在职场诸多方面取得的成就。其类别包括

  • 年度最佳雇主奖
  • 人力资源成就奖
  • 人力资源个人奖
  • 人力资源团队奖类
  • 解决方案提供商奖
  • 解决方案、实施和培训计划或媒体奖
  • 思想领导力奖类
  • 新冠疫情应对奖

这些奖项由 Stevie 奖颁发。 Stevie 奖组织了全球领先的商业奖项目中的八个,包括 International Business Awards®(国际商务奖)和American Business Awards®(美国商务奖)。

关于 Stevie 奖

Stevie 奖包括以下八大奖项:亚太地区 Stevie 奖、德国 Stevie 奖、中东和北非地区 Stevie 奖、American Business Awards®(美国商务奖)、International Business Awards®(国际商务奖)、Stevie “职业女性奖”、Stevie “杰出雇主奖” 以及 Stevie “销售与客户服务奖”。每年,Stevie 奖都会收到来自 70 多个国家/地区的 12,000 多个组织的参选报名。Stevies 旨在表彰全球范围内各种类型和规模的组织及其中的员工在工作中的杰出表现。若需了解更多有关 Stevie® 奖的更多信息,请访问: http://www.StevieAwards.com

第八届年度 Stevie “杰出雇主奖”由HiBob赞助。

市场营销联系人
Nina Moore
Nina@StevieAwards.com
+1 (703) 547-8389

此公告随附的照片可在以下网址查看:https://www.globenewswire.com/NewsRoom/AttachmentNg/06939e25-fba1-4760-aacd-ed60700c9173

Source: The Stevie Awards

HYTERA RELEASES LATEST DUAL-CHANNEL DMR AD-HOC REPEATERS

KUALA LUMPUR, Sept 18 (Bernama) — Hytera Communications, a global provider of professional communications technologies and solutions, has released E-pack200 and E-pole200, the latest ad-hoc network (WANET) repeaters, strengthening its offering of rapidly deployable two-way radio systems.

According to Hytera in a statement, both models support dual-channel and two-way networking to enable powerful on-demand connectivity, while E-pack200 is designed to be man-packable and E-pole200 can be installed at a fixed location.

Created narrowband ad-hoc multi-hop links through cascading and provided large coverage for voice, data and other services with two channels, the E-pack200 and E-pole200 are highly flexible in deployment and eliminate the need for wiring.

The ad-hoc repeaters are essential for public safety departments, as well as public protection and disaster relief (PPDR) agencies, to create, extend or enhance their private network coverage in remote areas, disaster sites and major events.

Both models support up to 31 nodes without central networking, whereby if one of the nodes fails or is damaged, the communication among other nodes remains unaffected.

The E-pack200 is equipped with a 148 watt-hours (Wh) removable battery, which is capable of supporting over eight hours of operation, while E-pole200 works with different power sources, such as solar and trunking base stations.

The compact size, networking flexibility and ease of installation for both repeaters bring a viable solution for removing blind spots of two-way radio networks on a temporary base or permanently in venues such as tunnels, underground garages and high-rise buildings.

— BERNAMA

CURIA 助力 REPLICATE BIOSCIENCE 新型下一代 RNA 疫苗的 I 期临床试验

根据 cGMP 生产的原料药供应助力 RBI-4000 新型自我复制 RNA (srRNA) 的首次人体临床研究

纽约州奥尔巴尼, Sept 14 (Bernama-GLOBE NEWSWIRE) — 领先的合同研究、开发和制造组织 Curia 今日宣布,其合作伙伴 Replicate Bioscience 已获得美国食品药品监督管理局 (FDA) 的研究性新药 (IND) 批准,并已在一项 I 期临床研究中为第一名参与者注射了 RBI-4000 自我复制 RNA (srRNA) 狂犬病疫苗,该研究使用了与 Curia 合作开发的临床材料。

Curia 进行了 srRNA RBI-4000 原料药的工艺开发、工艺放大和 cGMP 生产。这种 srRNA 大约有 10,000 个碱基,比传统的线性 mRNA 要大得多,历来难以按临床开发所需的规模生产。Curia 的分析方法开发和检测验证对于该 srRNA 分子的面世也至关重要。

Curia 研发部总裁 Christopher Conway 表示:“很荣幸 Curia 能成为生产这种新型 srRNA 技术的先驱,为我们的合作伙伴 Replicate 提供 RBI-4000 srRNA 原料药,以支持其 I 期临床试验。我们致力于为 mRNA 领域的客户提供从开发到 cGMP 生产的良好解决方案。”

与现有 mRNA 疫苗相比,这种新型 srRNA 疫苗有许多潜在改进,包括降低剂量要求和提高耐受性。这些提升也为 RNA 的进一步创新打开了大门,减少了 RNA 在疫苗和疗法应用中对分子大小的限制。

Replicate 创始人兼首席执行官 Nathaniel Wang 博士表示:“我们与 Curia 合作,制造了一类新型自我复制 RNA,与其他 RNA 技术相比,它有望展现出更好的生物活性、耐受性和疗效。Curia 扩大了长链 RNA 的生产工艺,实现了产量、纯度和效力并存的大规模生产,为 Replicate 的 I 期临床试验提供了支持。”

Curia 致力于成为从发现、开发到生产和商业化的首选合作伙伴,在药物开发生命周期的各个阶段提供全套服务,为小分子和大分子、原料药、药品无菌灌装/完成及实验室测试提供支持。

关于 Curia
Curia 前身为 AMRI,是一家领先的合同研究、开发和制造组织,为制药和生物制药客户从研发到商业生产提供产品和服务。Curia 在美国、欧洲和亚洲的 29 个地点拥有近 4,000 名员工,帮助其客户实现理念,开发治愈性产品。访问 CuriaGlobal.com,了解更多信息。

Curia 联系信息:
Viana Bhagan
+1 518 512 2111
corporatecommunications@CuriaGlobal.com

SOURCE: Curia Global, Inc.

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